The nervous system is responsible for our thoughts, our emotions, our senses, and our movements. The brain, nerves, and spinal cord are all members of this important process. How much do you know about the nervous system? Do you know what happens when the system malfunctions? Find out by taking this multiple-choice quiz.
1. The human nervous system is capable of a wide range of functions. What is the basic unit of the nervous system?
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Neurons are cells that perform most of the information processing, memory, and communication functions of the nervous system. Neurons are organized into circuits, also called neural pathways. These pathways are combined into structures that make up the nervous system. All the sensations, movements, thoughts, memories, and feelings come from signals passed along neural pathways. Glial cells surround the neurons and provide nutrients and structural support for them. The meninges are membranes that cover the brain and spinal cord. The cerebral spinal fluid surrounds the brain and spinal cord.
2. The neuron cell is made up of which of the following parts?
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Neurons have three basic parts: a cell body and two extensions called an axon and a dendrite. Within the cell body is a nucleus, which controls the cell's activities and contains the cell's genetic material. The axon looks like a long tail and transmits messages from the cell. Dendrites look like the branches of a tree and receive messages for the cell.
3. Neurons come in which different type(s)?
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The sensory neurons carry information from the sense organs (such as the eyes and ears) to the brain. Motor neurons have long axons and carry information from the central nervous system to the muscles and glands of the body. A third class of neurons is the interneurons. They only communicate with other neurons.
4. How do neurons communicate with one another?
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Neurons communicate with one another and with the organs they control by passing a minute electrical current called an "action potential." The action potential is caused by chemical stimulation of the neuron. Here's how it works. A small current flows along the cell membrane of a neuron to the end of the cell (the axon). The axon comes close to, but does not touch, the next neuron in the pathway. The tiny gap between neurons is called the "neural synapse." When the action potential reaches the end of the axon, the axon releases a chemical called a "neurotransmitter" into the synapse space. If the neighboring cell is a neuron, it receives the neurotransmitter through receptors called "dendrites." The receiving neuron's properties are changed by the neurotransmitter and a response occurs. The response can be to generate an action potential, which continues through the receiving cell's axons to the next neural synapse. The response could also be to stop an action potential.
5. What is a common neurotransmitter?
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Acetylcholine is an excitatory neurotransmitter, meaning it makes cells more excitable. It is found in the nerves in the body, where it stimulates muscles and glands. It is also found in the brain, where it helps regulate dopamine (another neurotransmitter) in the brain. Alzheimer's disease is associated with a shortage of acetylcholine. GABA is short for gamma-aminobutyric acid. It is an inhibitory transmitter, meaning it makes cells less excitable, and it helps the brain maintain muscle control. Serotonin is an inhibitory transmitter that helps the brain regulate acetylcholine.
6. Acetylcholine is a neurotransmitter that provides for communication between muscles and nerves. When there is a problem with the interaction between acetylcholine and the acetylcholine receptor sites on the muscles, which condition(s) can occur?
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In myasthenia gravis, the immune system creates an antibody that attacks acetylcholine receptors of the muscle cells. When acetylcholine binds to the acetylcholine receptors of the muscle cells, it causes them to contract. When an antibody blocks this binding, the cell fails to contract or contracts only weakly. This can cause drooping eyelids, weak eye muscles, and fatigue of affected muscles after exercise.
7. Dopamine is an important neurotransmitter. Which disease or disorder results when the neurons in the brain that produce dopamine die?
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Parkinson's is the result of the loss of dopamine-producing brain cells. Dopamine is a chemical messenger responsible for transmitting signals within the brain. Parkinson's disease occurs when certain nerve cells, or neurons, die or become impaired. Normally, these neurons produce dopamine. Loss of dopamine causes the nerve cells to fire out of control, leaving patients unable to direct or control their movement in a normal manner.
8. Certain metabolic diseases can affect the nervous system. For example, people with diabetes can develop a nervous system problem called diabetic neuropathy. What are the symptoms of diabetic neuropathy?
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An estimated 60 to 70 percent of people with diabetes have some form of neuropathy, but not all with neuropathy have symptoms. The highest rates of neuropathy are among people who have had the disease for at least 25 years. Symptoms may involve the sensory or motor nervous system, as well as the involuntary (autonomic) nervous system. Peripheral neuropathy causes either pain or loss of feeling in the toes, feet, legs, hands, or arms. Autonomic neuropathy causes changes in digestion, bowel and bladder function, sexual response, and perspiration. It can also affect the nerves that serve the heart and control blood pressure. Autonomic neuropathy can also cause hypoglycemia (low blood sugar) unawareness, a condition in which people no longer experience the warning signs of hypoglycemia.
9. Cerebral palsy affects neurons in which part of the body?
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Cerebral palsy is a term used to describe a group of chronic disorders impairing control of movement. They appear in the first few years of life and generally do not worsen over time. The disorders are caused by faulty development of or damage to areas in the brain that disrupts the brain's ability to control movement and posture. Symptoms of cerebral palsy include difficulty with fine motor tasks (such as writing or using scissors), difficulty maintaining balance or walking, and involuntary movements. The symptoms differ from person to person.
10. Which of the following is a genetic disease that causes neurons in the brain to waste away and die?
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Huntington's disease (HD) is a genetically programmed degeneration of brain neurons in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual abilities and emotional disturbances. HD is passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene.
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