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We inform our care with the following research efforts:
The Stanford BASE program brings together experts from multiple specialties across the Stanford University campus and its hospitals—including computational modeling, tissue engineering, genetics, and molecular biology—to create bold new solutions for children with heart disease.
The Marsden Lab at Stanford Engineering develops fundamental computational methods for the study of cardiovascular disease progression, surgical methods, treatment planning, and medical devices. It focuses on patient-specific modeling in pediatric and congenital heart disease, as well as adult cardiovascular disease. The lab bridges engineering and medicine through the department of Pediatrics, the department of Bioengineering, and the Institute for Computational and Mathematical Engineering. Research related to congenital heart disease includes exploring the ability to grow hypoplastic hearts.
The Michael Ma Lab at the Stanford University School of Medicine studies congenital heart disease and its surgical therapies. Computational fluid dynamics and ex-vivo biomechanical simulations are utilized to inform experiments and facilitate rapid translation to the operating room for immediate patient benefit. Ongoing collaborations focus on the development of medical devices to accelerate growth in hypoplastic valves and ventricles, as well as in individual patient-tailored planning and design of upcoming heart surgery.
SimVascular open-source software, used by Stanford Medicine; the University of California, Berkeley; the National Science Foundation; and other respected institutions, provides a way to capture medical images and patient data to create specific blood flow simulation and analysis models. The software and repository are used to simulate cardiovascular and pulmonary solid and fluid mechanics and to provide spatially and temporally resolved benchmark solutions that are used by academic, government, and industry researchers to verify their computational methods.
At Stanford Medicine Children’s Health, we’ve been performing research related to CCTGA for nearly two decades. Our researchers study various aspects of the complex care of CCTGA patients, including:
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